Abstract
Tracheal squamous papilloma (TSP) is the most prevalent type of benign tumor, accounting for 6%of all tracheal tumors including malignant tumors. TSP tends to present multiple tumors, and therefore the mainstay of treatment strategy is bronchoscopic intervention, except in malignant cases. We treated three cases of TSP between 1995 and 2010 : two female patients (49 and 54 y/o, both multiple TSP) and one male patient (67 y/o, solitary). One female case was associated with recurrent respiratory papillomatosis. The male patient underwent tracheoplasty because of suspected malignancy. Complete resection was performed and no recurrence was detected for five years. The two female cases underwent serial bronchoscopic electrosurgeries and laser ablations. In all cases pathologic examination revealed benign TSP. Human papilloma virus (HPV) infection was examined in one female case who presented recurrent respiratory papillomatosis, and the result was positive. By way of conclusion, the mainstay treatment for TSP is bronchoscopic intervention except in cases of malignancy. Association between TSP and HPV is obscure and further investigation is necessary.
