Studies of Correlation Between Physical Activity Levels and Endothelial Function of Obese Postmenopausal Women

Abstract

Research purposes: Estrogen decreased levels in postmenopausal women, cause the body function changes significantly, and the special crowd obese postmenopausal women we should pay more attention. Therefore, this research observed the correlation between physical activity levels and vascular endothelial cell function of obese postmenopausal women. Explore the role of different physical activity intensity for vascular endothelial cell function of obese postmenopausal women.

Subject and Methods: 45-60 years old obese postmenopausal women, natural menopause more than five years, no malignant gynecological disease, no smoking, no cardiovascular disease, without taking antioxidants, involved in this experiment before fully understand the experiment content and experiment process, and signed the informed consent.

Methods: At the beginning, fill in the international physical activity questionnaire and self-made questionnaire; BMI according to 《the overweight and obesity prevention guide of Chinese adults》 BMI >28 kg/m 2 for obesity is divided into three groups, 20 people/group; Blood pressure test using blood pressure meter; FMD (flow mediated dilation), endothelial function test using UNEX EF detector; lipid test by fasting venous blood.

Results: age: Low intensity group (LG) 53±6.5 (years), moderate intensity group (MG) 54±4.2 (years), high intensity group (HG) 52±5.6 (years), height: low intensity group 154.3±4.0 (cm) and moderate intensity group 153.3±3.2 (cm), high intensity group 156.4±4.7 (cm). Weight: low intensity group 73.9±8.8 (kg), moderate intensity group 69.4±6.7 (kg), high intensity group 74.8±7.6 (kg). BMI: low intensity group 31.0±3.4 (kg/cm2) and moderate intensity group 29.5±4.6 (kg/cm2), high intensity group 30.6±3.7 (kg/cm2); Level of physical activity: low intensity group 417.3±156.5 (MET-min/week), moderate intensity group 2,417.3±546.5 (MET-min/week), high intensity group 7,417.3±878.9 (MET-min/week). Endothelial function: low intensity group 7.9±2.8 (%), moderate intensity group strength in the group of 7.8±2.8 (%), high intensity group 8.8±3.5 (%). Age, height, weight, BMI: we had a match between groups, so the groups does not appear significant difference. Correlation of physical activity levels and endothelial function: low intensity and high intensity group (p<0.05), there was no statistical significance between several other groups.

Conclusion: High intensity physical activity can have certain effect in obese postmenopausal women, low and moderate intensity physical activity does not show the obvious effect. So high intensity physical activity has certain effect on endothelial function in obese postmenopausal women, specific mechanism needs further research.