Abstract
The clinical characteristics and results of surgical treatment in patients with double carcinomas of the lung and other organs were evaluated using 73 patients with pathologically confirmed double carcinomas out of a total of 1279 lung carcinoma patients resected from 1980 to 1996. The double carcinomas were divided into three groups according to anatomical conditions and environmental factors including smoking habits; Group A; laryngopharynx and esophagus; Group B: gastroduodenum, hepatopancreas, kidney and urinary bladder; Group C : colorectum, breast, uterus and other organs. Clinical features revealedsignificant differences in the gender distribution and smoking indices of Groups A, B and C. The re-occurrence interval also demonstrated a significant difference between Groups A and C. However, no significant differences were observed in age distribution, the histologic types of the lung carcinoma, or the pathological stages of the lung carcinoma. The overall 5-year survival rates from lung resection inGroups A, B and C were 61.5%, 46.6% and 68.7%, respectively. There was a significant difference between Groups B and C (p<0.05) in terms of logrank test. The survival rate in patients with synchronous double carcinomas was worse than that in metachronous double carcinoma patients who subsequent-ly had resected lung carcinoma. Smoking habits is considered to be strongly related to double carcinomas of the lung, the laryngopharynx and the esophagus, and a surgical treatment for lung carcinomas is a promising modality to increase survival in patients with such double carcinomas.
