Abstract
In mesoscopic region, molecular machines are defined as machines using stochastic resonance (SR) and described as complex diffusion equations. Appropriate adjusted diffusion coefficients and corresponding mass terms can describe many phenomena caused by mechanism of Brownian motions and Markov process. If the molecular machines do not have SR, the molecular machines do not efficiently work out under fluctuational environments. Molecular machines can live together with thermal fluctuations of their environments. We proposed stochastic machines (SIRM) using SR existing between myosin head and random motions of water molecules. SR means coordinated movements of molecular structures and coherent sates of machines.