Radiation Imaging of Magnetic Nano-Particle Fluid in a Mouse Body

Abstract

Magnetic fluid is composed of nano-meter size particles. Magnetic Targeting Drug delivery System (MT-DDS) which uses magnetic fluid attracts a great deal of attention as one of most advanced medical treatments especially for cancers. Since it needs a real-time monitoring system, we investigated its observation properties in a mouse body with X-ray imaging at Spring-8 in this study. As a result, we found it is possible to extract the density distribution of magnetic fluid in mouse body. Moreover, we demonstrated that optimization of digital values of imaging data can make the contrast better, which suggests possibility of real-time imaging system for MT-DDS.