抄録
A case of parathyroid carcinoma associated with recurrent gastric ulcer was presented. The excretion of nephrogenous c-AMP, calcium, phosphate and magnesium, and serum levels of PTH, calcium, phosphate and magnesium were determined before and after parathyroidectomy.
Nephrogenous c-AMP and plasma N-PTH levels decreased rapidly to normal values within thirty minutes after removal of the tumor, though it took 15 hours for plasma levels of C- and M-PTH and serum calcium concentration to become normal. Excretion of urinary phosphate also decreased rapidly, indicating rapid disappearance of PTH action in the kindey. Therefore, nephrogenous c-AMP was shown to a good indication of biological activity of parathyroid hormone.
Gastric ulcer healed with no anti-ulcer medication after the surgery and the patient has been well without recurrence of the ulcer. There was neither hyperacidity of gastric juice nor hypergastrinemia before surgery. Hyperparathyroidism or hypercalcemia per se may have played the major role in the occurrence of gastric ulcer.
