A Novel Treatment for Pediatric Extensive Burns with Good Outcomes Using Artificial Dermis and Autologous Cultured Epidermal Grafting －A Case Report－

Abstract

 Extensive pediatric burns easily become severe due to complications such as toxic shock syndrome and sepsis. Wound observation without skin grafting for an extended period of time is considered to hold higher risk in pediatric patients than adults. Autologous split-thickness skin grafting is often performed for early wound closure. For the pediatric population, frequent procedures and interventions are required to accommodate their growth and development, which further complicate the treatment plans for both wound size reduction and closure.
 In this case report, we managed a one-year-old child with extensive burn who was treated by constructing a wound bed of dermis-like tissue with artificial dermis. The burn was closed by transplantation of autologous culture epidermis instead of split-thickness skin graft. Although the utilization of autologous cultured epidermal transplantation for children under two years of age has not been established, our findings strongly suggest the need for further multi-center clinical studies to investigate this possibility.