Therapeutic Experience of Patients with Extensive Burns using Negative Pressure Wound Therapy for Wound Bed Preparation of Autologous Cultured Epidermis（JACE^®）Skin Grafts

Abstract

 Good bed preparation for burn wounds is necessary to obtain good graft attachment for the achievement of wound closure. The same wound bed preparation is also important for autologous cultured epidermal grafts. At our hospital, we use local negative pressure closure as a matrix formation technique for autologous cultured epidermis (JACE^®) skin grafts in patients with extensive burns. We experienced six cases between January 2015 and December 2022 in which a high live implantation rate of > 80% was achieved. Local closed negative pressure therapy may be useful for wound bed preparation for autologous cultured epidermal transplantation.