2022 年 28 巻 1 号 p. 1-5
Left main trunk coronary artery disease is a serious life-threatening condition which require proper medical treatment. This time we have reviewed randomized control trial comparing percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG). In four major study (EXCEL, NOBLE, SYNTAX, and PRECOMBAT), revascularization rate was more frequent in PCI. However, rate of myocardial infarction (MI) was different on each study, probably because the difference of definition of MI. Meta-analysis using individual patient data, the occurrence of MI during follow-up and the necessity of coronary revascularization were significantly higher in the PCI group compared to the CABG group.