Journal of Coronary Artery Disease
Online ISSN : 2434-2173
Review Articles
How and When to Use Fractional Flow Reserve in Coronary Artery Bypass Grafting
Jun TakakiTakashi YoshinagaKen OkamotoHideaki HidakaTatsuya HoribeTakafumi HirotaKosuke NakataToshihiro Fukui
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JOURNAL OPEN ACCESS

2025 Volume 31 Issue 2 Pages 39-45

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Abstract
It is recommended that the degree of ischemia be evaluated using fractional flow reserve (FFR) before deciding whether to perform percutaneous coronary intervention (PCI) if the degree of stenosis is moderate on coronary angiography. In large trials, FFR-guided PCI was shown to significantly reduce the rates of death, myocardial infarction, and emergency revascularization in comparison to medical therapy alone. However, the effectiveness of using the FFR in coronary artery bypass grafting (CABG) remains controversial. Some studies reported the effectiveness of using the FFR in terms of graft patency. Others reported that it was not effective. The greatest advantage of CABG is that it allows for complete revascularization in a single operation and has a preventive effect against the development of new lesions. This is the most effective revascularization method for multivessel coronary artery disease. In the future, it is believed that the effective use of the FFR and consideration of optimal revascularization by the heart team will further improve patient quality of life.
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© 2025 The Japanese Coronary Association

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