REMOVAL ESTIMATION OF MIDDLE MOLECULAR SUBSTANCES (MM) WITH HIGH SPEED LIQUID CHROMATOGRAPHY

KIYOTAKA SAKAI; SHINGO TAKESAWA

doi:10.1252/jcej.18.8

KIYOTAKA SAKAI, SHINGO TAKESAWA

著者情報

キーワード: Hemodialysis, High Speed Liquid Chromatography, Middle Molecules, Pool Model, Cell Membrane Clearance

ジャーナルフリー

1985 年 18 巻 1 号 p. 8-13

DOI https://doi.org/10.1252/jcej.18.8

詳細

抄録

Middle molecules, which are contained in the blood of chronic renal failure patients, can be detected by using high-speed liquid chromatography. Analysis of blood or dialysate with HSLC is completed within 35 minutes. Application of a two-pool model for the body water of the patients clearly indicates that MM has a tendency to be removed mainly from extracellular space.

責任著者(Corresponding author)

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