Abstract
Engineering problems in applying immobilized biocatalysts to the production of useful materials are discussed. The scope of the review covers immobilized enzymes, immobilized microorganisms, immobilized mammalian cells, immobilized plant cells and the use of membranes for immobilization. Recent developments in these subjects are reviewed especially as to reaction analyses, mass-transfer effects, bioreactions using an organic phase and problems concerning reactor design. The future scope of research in this field is briefly described in the final section.