Treatment and Pathophysiology of Clinoidal Meningiomas

Abstract

  Parasellar meningioma is a general term for meningiomas originating from the vicinity of the sella turcica. Because of the critical structures in this area, the displacement of the surrounding structures must be considered. This study discusses anterior clinoid meningiomas that occur in the parasellar region of the eye.

  Anterior clinoid meningiomas are classified as caudal, craniolateral, or medial. The most common symptom is visual deterioration, followed by headache. The deterioration of visual function may be attributed to the extension of the tumor into the optic canal. Surgical resection is the first-choice treatment. A pterional approach is usually selected for removing the anterior clinoid process and early decompression of the optic nerve. Stereotactic radiosurgery or radiotherapy results in good tumor control rates. Boron neutron capture therapy for high-grade meningiomas, currently in the clinical trial phase, is expected to be implemented in the future.