Abstract
Background: Reducing ischemia is an important therapeutic goal in patients with coronary artery disease. We investigated the relationships between stress myocardial perfusion imaging (MPI) before and after percutaneous coronary intervention (PCI) and the cardiac events and revascularization. Methods and Results: We retrospectively analyzed 111 patients who underwent PCI (PCI group) from 2008 to 2012 and who underwent stress MPI before treatment and for 3–30 months (mean, 313 days; median, 239 days) after treatment. The extent of ischemia observed on stress MPI before treatment was improved after PCI. The major cardiac events were observed in 11 patients (9.9%) and the rate of revascularization was 28.8% during follow-up period. Major adverse cardiac events were influenced by ischemia on second MPI and revascularization was influenced by ischemia on second MPI and HDL-cholesterol levels. 59.3% of cases underwent revascularization were not related to restenosis of primary lesions. Conclusions: Stress MPI after PCI may be useful for assessing myocardial ischemia by detecting restenosis, the progression of residual stenosis, and new lesions within the coronary artery in patients after PCI.