Aim: We sought to clarify the clinical features and prognostic factors of acute decompensated heart failure (ADHF) based on its etiology. Method and Results: From July 2006 to June 2010, consecutive 757 ADHF patients were examined and divided into ischemic heart disease group (IHD), valvular heart disease group (VHD) and non-ischemic non-valvular heart disease group (NINVHD). In hospital mortality, IHD, VHD and NIV were 3.4%, 4.5%, and 5.8% respectively. There were higher in gender, age, prevalence of hypertension, hyperlipidemia and, diabetes in IHD than non-IHD (VHD and NINVHD). But the prevalence of arterial fibrillation lower in IHD than non-IHD. Long term mortality did not differ among the groups. Multivariate analyses revealed significant determinants of long term mortality were diabetes and smoking in IHD, hypertension and serum Na level in VHD, hypertension, serum creatinine and plasma BNP levels in NIV. Conclusion: Long-term mortality of patients with ADHF was comparable in terms of its etiology; however, the prognostic factors vary according to the underlying diseases.
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