Abstract
Aims: The purpose of this study was to clarify clinical characteristics due to difference of physical function and the factors related to physical function in patients with heart failure (HF) with preserved ejection fraction (HFpEF).
Methods: This retrospective cohort study comprised 310 patients with HF aged ≥ 65 years who were hospitalized acute decompensated heart failure (ADHF) between November 2017 and October 2021. We investigated age， sex， body mass index (BMI)，length of hospital stay，rehabilitation start day，New York Heart Association (NYHA) class，comorbidity，long-term care insurance，medication，cardiac/renal function，hemoglobin，Nutrition，maximal quadriceps isometric strength (QIS)，grip strength，Short Physical Performance Battery (SPPB)，and Functional Independence Measure (FIM)，and investigated their relationship with physical function.
Results: 78 HFpEF patients who met the inclusion criteria participated in this study，used SPPB，which is an index of physical function，we classified them into two groups，high physical performance group (10-12 points: n=25)，and low physical performance group (0-9 points: n=53)，based on the score at discharge. As a result of logistic regression analysis，age and Geriatric Nutritional Risk Index (GNRI) were extracted as independent factors related to physical function.
Conclusions: It was revealed that the characteristics of HFpEF patients with low physical function are older， malnutrition.
