2012 年 54 巻 4 号 p. 199-205
About one-third of all proteins are metalloproteins, which play fundamental roles in nature. In particular, FeS proteins are the most ubiquitous and represent diverse functions such as electron transfer, enzyme reaction and gene expression. Metal ions are precisely delivered to the target proteins by specific carrier proteins (metallochaperone). This review will describe the crystal structures of the oxidative stress sensor SoxR, and [NiFe] hydrogenase maturation proteins.