日本結晶学会誌
Online ISSN : 1884-5576
Print ISSN : 0369-4585
ミニ特集 キラリティー測定の最前線
放射光真空紫外円二色性分散計の開発と生体分子構造解析
松尾 光一
著者情報
ジャーナル フリー

2018 年 60 巻 4 号 p. 200-208

詳細
抄録

A vacuum-ultraviolet circular-dichroism spectroscopy using synchrotron radiation greatly expands the utility of chiroptical technique for the structural analysis of biomolecules by combining with theoretical analysis and bioinformatics. This spectroscopy provides the structural dynamics, intramolecular hydrogen bonds, and hydrations of saccharides, and also successfully estimates the secondary structure contents, numbers of segments, and sequences of native proteins and non-native proteins such as membrane-bound proteins. The circular dichroism theory of protein discloses the local structures of the amyloid fibrils at the molecular level. This synchrotron-radiation spectroscopy is opening a new filed in the glycobiology and structural biology.

著者関連情報
© 2018 日本結晶学会
前の記事 次の記事
feedback
Top