特集 X線の次
BioSAXSを活用した生体高分子の溶液構造状態推定
2023 年 65 巻 1 号 p. 42-50
詳細
2023 年 65 巻 1 号 p. 42-50
Small-angle X-ray scattering（SAXS）for solution samples of biological macromolecules, recently called BioSAXS, has been used to estimate the conformational state of flexible proteins and unstable protein complexes in solution. With the advent of a new technique called SEC-SAXS, it has become easier to obtain structural information derived only from the target molecule, and it is now possible to estimate the structural state in solution with higher accuracy than 10 years ago. In this article, I will introduce not only some characteristic examples of BioSAXS analysis, but also the recently developing technique of time-resolved measurement.
