トリプトファンとピリジン, フラビンおよびチアミン補酵素との芳香環相互作用の構造化学

抄録

This article briefly deals with the interaction modes between the indole ring of tryptophan and the aromatic rings of pyridine, flavin and thiamin coenzymes on the basis of the crystal structures of these model compounds or complexes. The obtained insights would be important in order to elucidate the physiological functions of tryptophan derivatives in living cell. It appears to be a characteristic of tryptophan derivatives that the electron-donating indole ring associates with the biologically important aromatic rings through the prominent π-π stacking, partly charge-transfer, interaction.