Abstract
The authors report a case of osteomeylitis of the femur associated with palmoplantar pustulosis. A 48-year-old woman and the chief complaint were left thigh pain and palmar eruption. There was no abnormality on plain roentgenographs at the time of the first examination. The pus of palmar eruption was clear. The patient did not have a history of psoriasis and did not use oral steroids before then. The destructive thinning image suggests periostial reaction appeared inside the left femur through the plain roentgenograph of one month later. Trabecular bone was destroyed in pathological study. Permeation of organization ball and neogenesis of capillary vessels also appeared. Treatment with the antibiotic (MINO 200mg/a day) was performed and the symptom was reduced. At the same time, palmar eruption was diagnosed as palmoplantar pustulosis in pathological study. Department of dermatology also did a treatment for the palmoplantar pustulosis in parallel, and it also became light.
With this case, immunological test of those other than a HLA antigen was not performed and the generating mechanism is unclear. The authors think that there may be a close relation between osteomeylitis of the femur and palmoplantar pustulosis cause they generated at the period and became light in parallel. When condition gets worse, the authors think that tonsillectomy may be needed from an immunology view point.
