抄録
We present our experience with one case of Slipped Capital Femoral Epiphysis (SCFE) with panhypopituitarism. The patient was a 27 years old male who was born with fetal distress and had low body height during childhood. At 18 years of age, he was admitted to our hospital because of growth retardation with lack of secondary sex characters, and was diagnosed with panhypopituitarism. He was administered growth hormone, thyroxine, cortisone and HCG-HMG. At 27 years of age, he suffered left hip pain with positive Drehmann's sign and was diagnosed as having the left SCFE. On blood test, LH, FSH, and testosterone were low, but free T4 and GH were within normal limit. Posterior tilting angle (PTA) of the femoral epiphysis was 6° at the right side, and 44° at the left. Southwich osteotomy was performed on the left hip and in-situ pinning was done on the right hip. Three months after the surgical operation, he could walk without pain and Drehmann's sign disappeared. PTA of the left femoral epiphysis as measured on X-ray was 30°. This case of SCFE suggests that imbalance of sex-steroid hormones and growth hormone may induce the disintegration of epiphysial growth plate of femoral head.