Abstract
A fluoride mouthrinse is necessary to promote oral health planning for the prevention of enamel and root surface caries throughout life. The aim of this study is to estimate fluoride (F) uptake to human enamel and root surfaces with two F mouthrinses available (FMOB ; ORABLISS®, FMMR ; MIRANOL® ) in vitro. To determine F uptake to enamel and root surfaces with various F concentrations of mouthrinse, enamel and root surface blocks were immersed with starring in 250 ppm and 450 ppm solutions of F mouthrinse at 37℃ for 24 hr. After fixation with 50 mM primary calcium phosphate (saturated, pH 7.4) and washing with distilled water, surface sampling was performed with 0.5 M HCl0_4 at 5, 10, 15, 30, 60 and 120 sec. The results were as follows ; 1) F concentration in enamel and root surfaces in the two F mouthrinse groups (250 ppm, 450 ppm, pH 5.5) showed a significantly higher value than that of each control group (p < 0.05). 2 ) F concentration profile in enamel with each 450 ppmF solution was approximately twice as high as that of the 250 ppmF solution in the first layer (2 μm). F uptake was almost similar in the 2 nd layer. 3 ) F concentration to the root surface with F mouthrinse was significantly twice as high as that of enamel at 20 μm depth (p < 0.05). These results suggest that fluoride mouthrinses are promising preventive measures for root surface caries in the adult population in terms of a clearly higher fluoride uptake in in vitro assessment.
