Journal of Epidemiology
Online ISSN : 1349-9092
Print ISSN : 0917-5040
ISSN-L : 0917-5040
Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study
Atsushi HozawaKozo TannoNaoki NakayaTomohiro NakamuraNaho TsuchiyaTakumi HirataAkira NaritaMana KogureKotaro NochiokaRyohei SasakiNobuyuki TakanashiKotaro OtsukaKiyomi SakataShinichi KuriyamaMasahiro KikuyaOsamu TanabeJunichi SugawaraKichiya SuzukiYoichi SuzukiEiichi N KodamaNobuo FuseHideyasu KiyomotoHiroaki TomitaAkira UrunoYohei HamanakaHirohito MetokiMami IshikuroTaku ObaraTomoko KobayashiKazuyuki KitataniTakako Takai-IgarashiSoichi OgishimaMamoru SatohHideki OhmomoAkito TsuboiShinichi EgawaTadashi IshiiKiyoshi ItoSadayoshi ItoYasuyuki TakiNaoko MinegishiNaoto IshiiMasao NagasakiKazuhiko IgarashiSeizo KoshibaRitsuko ShimizuGen TamiyaKeiko NakayamaHozumi MotohashiJun YasudaAtsushi ShimizuTsuyoshi HachiyaYuh ShiwaTeiji TominagaHiroshi TanakaKotaro OyamaRyoichi TanakaHiroshi KawameAkimune FukushimaYasushi IshigakiTomoharu TokutomiNoriko OsumiTadao KobayashiFuji NagamiHiroaki HashizumeTomohiko AraiYoshio KawaguchiShinichi HiguchiMasaki SakaidaRyujin EndoSatoshi NishizukaIchiro TsujiJiro HitomiMotoyuki NakamuraKuniaki OgasawaraNobuo YaegashiKengo KinoshitaShigeo KureAkio SakaiSeiichiro KobayashiKenji SobueMakoto SasakiMasayuki Yamamoto
Author information
JOURNALS OPEN ACCESS Advance online publication
Supplementary material

Article ID: JE20190271

This article has a public article.
Details
Abstract

Background: We established a community-based cohort study to assess the long-term impact of the Great East Japan Earthquake on disaster victims and gene-environment interactions on the incidence of major diseases, such as cancer and cardiovascular diseases.

Methods: We asked participants to join our cohort in the health check-up settings and assessment center based settings. Inclusion criteria were aged 20 years or over and living in Miyagi or Iwate Prefecture. We obtained information on lifestyle, effect of disaster, blood, and urine information (Type 1 survey), and some detailed measurements (Type 2 survey), such as carotid echography and calcaneal ultrasound bone mineral density. All participants agreed to measure genome information and to distribute their information widely.

Results: As a result, 87,865 gave their informed consent to join our study. Participation rate at health check-up site was about 70%. The participants in the Type 1 survey were more likely to have psychological distress than those in the Type 2 survey, and women were more likely to have psychological distress than men. Additionally, coastal residents were more likely to have higher degrees of psychological distress than inland residents, regardless of sex.

Conclusion: This cohort comprised a large sample size and it contains information on the natural disaster, genome information, and metabolome information. This cohort also had several detailed measurements. Using this cohort enabled us to clarify the long-term effect of the disaster and also to establish personalized prevention based on genome, metabolome, and other omics information.

Information related to the author
© 2020 Atsushi Hozawa et al. This is an open access article distributed under the terms of Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
feedback
Top