This article has now been updated. Please use the final version.
https://orcid.org/0000-0002-8031-8523
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
https://orcid.org/0000-0002-1264-0684
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University School of Medicine, Iwate Medical University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Saitama Prefectural University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
https://orcid.org/0000-0003-2585-2405
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Tohoku University Hospital, Tohoku University
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University School of Medicine, Iwate Medical University
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University School of Medicine, Iwate Medical University
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University School of Medicine, Iwate Medical University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University International Research Institute of Disaster Science, Tohoku University
https://orcid.org/0000-0002-3080-6107
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Teikyo University School of Medicine
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Radiation Effects Research Foundation
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Tohoku University Hospital, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Tohoku University Hospital, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Ageo Central General Hospital
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Tohoku University Hospital, Tohoku University International Research Institute of Disaster Science, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Tohoku University Hospital, Tohoku University International Research Institute of Disaster Science, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Faculty of Medicine, Tohoku Medical and Pharmaceutical University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Tohoku University Hospital, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Setsunan University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University Institute for Biomedical Sciences, Iwate Medical University
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Dentistry, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University International Research Institute of Disaster Science, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Tohoku University Hospital, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University International Research Institute of Disaster Science, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Tohoku University Hospital, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Institute of Development, Aging and Cancer, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Graduate School of Information Sciences, Tohoku University Kyoto University Graduate School of Medicine Faculty of Medicine
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Center for Advanced Intelligence Project, RIKEN
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Institute of Development, Aging and Cancer, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Miyagi Cancer Center
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Tohoku University Hospital, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Tokyo Medical and Dental University
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University School of Medicine, Iwate Medical University
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University School of Medicine, Iwate Medical University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University The JIKEI University School of Medicine
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University School of Medicine, Iwate Medical University
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University School of Medicine, Iwate Medical University
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University School of Medicine, Iwate Medical University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University Iwate Medical University School of Nursing
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University Institute for Biomedical Sciences, Iwate Medical University
https://orcid.org/0000-0001-5626-0184
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University School of Medicine, Iwate Medical University
Iwate Medical University
https://orcid.org/0000-0001-8529-6688
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University School of Medicine, Iwate Medical University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Tohoku University Hospital, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Information Sciences, Tohoku University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University Tohoku University Hospital, Tohoku University
Iwate Medical University
Graduate School of Medicine, Tohoku University
Iwate Medical University
Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University Institute for Biomedical Sciences, Iwate Medical University
Tohoku Medical Megabank Organization, Tohoku University Graduate School of Medicine, Tohoku University
Article ID: JE20190271
(compatible with EndNote, Reference Manager, ProCite, RefWorks)
(compatible with BibDesk, LaTeX)
Background: We established a community-based cohort study to assess the long-term impact of the Great East Japan Earthquake on disaster victims and gene-environment interactions on the incidence of major diseases, such as cancer and cardiovascular diseases.
Methods: We asked participants to join our cohort in the health check-up settings and assessment center based settings. Inclusion criteria were aged 20 years or over and living in Miyagi or Iwate Prefecture. We obtained information on lifestyle, effect of disaster, blood, and urine information (Type 1 survey), and some detailed measurements (Type 2 survey), such as carotid echography and calcaneal ultrasound bone mineral density. All participants agreed to measure genome information and to distribute their information widely.
Results: As a result, 87,865 gave their informed consent to join our study. Participation rate at health check-up site was about 70%. The participants in the Type 1 survey were more likely to have psychological distress than those in the Type 2 survey, and women were more likely to have psychological distress than men. Additionally, coastal residents were more likely to have higher degrees of psychological distress than inland residents, regardless of sex.
Conclusion: This cohort comprised a large sample size and it contains information on the natural disaster, genome information, and metabolome information. This cohort also had several detailed measurements. Using this cohort enabled us to clarify the long-term effect of the disaster and also to establish personalized prevention based on genome, metabolome, and other omics information.