歯科用局所麻酔薬の局所麻酔効果および歯髄の血流動態に関する研究

抄録

Abstract : The aims of this study were to investigate the effects of on pulpal blood flow and anesthesia in human teeth during dental local anesthesia using either 2% lidocaine with epinephrine (Xylocaine) or 2% lidocaine with epinephrine bitartrate (Ora).

 The duration of anesthesia and the occurrence of a reduction in blood flow were examined in the dental pulps of maxillary central incisor teeth. The local anesthetic solution was injected into the soft tissues adjacent to the apex of the sound maxillary incisor tooth. The pulpal blood flow was monitored by a laser Doppler flowmeter. At selected times, pulpal anesthesia was tested with an electric pulp tester.

 Following injection of 0.5 ml of dental local anesthetic solutions, the reduction of pulpal blood flow were 45. 4% (Xylocaine) and 51.6% (Ora). The duration of reduced blood flow were 34 min (Xylocaine) and 39 min (Ora). The duration of pulpal anesthesia were 74 min (Xylocaine) and 70 min (Ora).

 This study indicated that there was no significant difference on the effects of between 2% lidocaine with epinephrine and 2% lidocaine with epinephrine bitartrate.