1998 年 19 巻 1 号 p. 64-66
Abstract : To confirm the safety of the HY-c cement, including tannin agent, in use as a root canal sealer, we showed in a previous report that the experiment in vitro, which indicate the safety in tissue culture.
But some unknown points of the reaction of a living body in the state of the direct contact to that still remained. Therefore, the experiment in vivo of this time was performed.
At first, the HY-c cement was directly implanted into the muscle of Balb mice.
Then, the mice were sacrificed after 2 or 5 weeks, and the tissue reactions were examined with a microscope. It showed that any inflammation on the tissue was not observed. That result indicated that the safety of this agent was confirmed also in vivo.
We expect that this tannin agent will play a great role in saving teeth.