Abstract
A sensitive and selective method was developed for the determination of amitrole in environmental water samples using by liquid chromatography/tandem mass spectrometry (LC/MS/MS) . Trace amount of amitrole was collected on Sep-Pak Plus AC-2 cartridge (AC-2 cartridge) and eluted with 10 ml of 25 % ammonia water/chloroform/acetonitrile (10/9/81) . The elute was separated by reversed-phase liquid chromatography and determined by tandem mass spectrometry. The collection efficiency of amitrole on AC-2 cartridge was from 97 % to 100 %. The detection limit of amitrole was 0.001 μg/l, and relative standard deviations of repeated analysis in 0.0025 μg/l-0.01μg/l of sample were in the range of 6.9-8.0 %. Amitrole was detected at 0.004 μg/l level in the river water and 0.6 μg/l level in leachate from waste landfills.
