Abstract
Mutagenicity of 15 diaminodiphenylmethane and related compounds used or synthesized as epoxy resin hardner, many of which were 4, 4'-diamino-diphenyl derivatives, were examined by Ames preincubation assay using Salmonella typhimurium TA98 and TA100 in both absence and presence of metabolic activation system (S9 mix) . 8 compounds showed the mutagenicity in the presence of S9 mix. Mutagenic activities decreased according to the increase of the molecular weight. It was suggested that the mutagenicity of aromatic amines synthesized as epoxy resin hardner were affected by the type and the position of substituent and by their formula weight.
