2016 Volume 10 Issue 3 Pages 195-201
In order to clarify the current situation regarding drug-induced photosensitivity in Japan, we conducted database searches for such cases using the Japanese Adverse Drug Event Report database (JADER) . Among the cases recorded in the JADER, we targeted "photosensitivity reaction" , "solar dermatitis" , "photodermatosis" , and "actinic cheilitis" , and analyzed the patients' backgrounds, the drugs used, the date of onset, and outcomes.
The total number of reported cases was 293 (males : 160, females : 133) , with elderly patients (60s : 75, 70s : 83) comprising the largest group. The most frequently reported drug suspected to have been the cause was losartan potassium-hydrochlorothiazide combination (72) , followed by ketoprofen (25) . Drug-induced photosensitivity tended to occur between April and August. Although no improvements were seen in some cases, many others did show improvement.
Our survey was able to reveal the situation associated with onset of drug-induced photosensitivity, which will aid the prevention and treatment of this condition.
