It is important to simulate and control macro compositional segregation of alloyed elements, in order to produce large ingots for forging and VAR(Vacuum Arc Remelting) ingots with high quality and reliabilty. In this study, a simulation model which uses database for thermodynamic calculation, solidification analysis and material balance calculation by solute redistribution during solidification was developed and applied for large ingots made of 2.25 Cr-1Mo steel (190t), 3.5NiCrMoV steel (180t), 3.0NiCrMoV steel (420t) and Ti-Pd alloy VAR ingot. The calculated results proved to be in excellent agreement with the experimental results, and the simulation model was proved to be suitable for manufacturing.