The Journal of General and Applied Microbiology
Online ISSN : 1349-8037
Print ISSN : 0022-1260
ISSN-L : 0022-1260
Invited Reviews
Isolation of new actinomycete strains for the screening of new bioactive compounds
Yoko TakahashiSatoshi Omura
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2003 Volume 49 Issue 3 Pages 141-154

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Abstract

In order to facilitate the discovery of novel bioactive compounds from microorganisms, various techniques for isolation of new actinomycete strains have been attempted. Studies of the vertical distribution of actinomycetes in soil, isolation of actinomycetes from desert soils or fallen leaves, selective isolation of Kitasatospora strains using novobiocin or Actinoplanes strains using the chemotactic method, and the use of gellan gum as a solidifying agent were carried out. We discovered 9 novel bioactive compounds from actinomycete strains isolated under unusual conditions, and proposed two new genera, five new species and one new subspecies.

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© 2003 by The Applied Microbiology, Molecular and Cellular Biosciences Research Foundation
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