SOME CONSIDERATION ON THE RATE OF INDUCED ALDOLASE SYNTHESIS IN AZOTOBACTER VINELANDII

Abstract

The rate of induced enzyme synthesis was formulated in general terms in line with a new account of the operon model by Yagil et al. who assumed originally two kinds of intracellular equilibria, one dealing with an effector (inducer) and free repressor, and the other, an operator and free repressor.
The rate of induced aldolase synthesis in Azotobacter vinelandii was examined during the unsteady state realized by a stepwise change in rotation speed of an impeller in a chemostat culture of this specific bacterium. Some of the observations, exhibiting incidentally the first-order response time, were in compliance with an analytical solution of the above-mentioned formula, taking dissolved oxygen in the culture medium as an inducer. The first-order response in the rate of induced aldolase synthesis was given a new interpretation.