Abstract
Saccharomyces cerevisiae requiring pantothenic acid, biotin, and inositol decreased in respiratory capacities, such as respiration rate and cytochrome contents, only by the deficiency of pantothenic acid. This decrease was effective compared to glucose repression and recovered in a short time by the addition of pantothenic acid. Simultaneously, the deficient cells were free of fully developed mitochondria and possessed only primitive envelopes with a poor inner membrane, and the mitochondrial development was induced by the addition of pantothenic acid. The development of mitochondrial membrane structure was roughly parallel to the biosynthesis of cytochromes after the addition of pantothenic acid.
