1975 Volume 21 Issue 6 Pages 335-343
Adenylate cyclase from Coprinus macrorhizus was found in the particulate fractions containing plasma membrane, microsomes, and mitochondria. Glucose addition lead to inhibition of adenosine 3′:5′-cyclic monophosphate accumulation and fruiting body formation in vivo, but glucose did not inhibit the adenylate cyclase activity in vitro. The enzyme was solubilized by treatment with detergents or KCl. The localization of adenylate cyclase did not change in the course of fruiting body formation under various light conditions.