RELATIONSHIP BETWEEN CELL MORPHOLOGY AND THE TYPES OF DIAMINOPIMELIC ACID IN KITASATOSPORIA SETALBA

Abstract

The relationship between cell morphology and the type of 2, 6-diaminopimelic acid (A₂pm) in Kitasatosporia setalba was studied in a submerged culture. When a strain of K. setalba was cultivated in a liquid culture with shaking, it produced two kinds of cells, spore-like cells and filamentous mycelia, which are morphologically distinct from each other. The former contained LL-A₂pm, and the latter meso-A₂pm. A time course study in a submerged culture inoculated with the spore-like cells demonstrated that each type of A₂pm detected in K. setalba is clearly associated with one of the two forms of cell.