Abstract
To investigate changes of protein profiles and appearance of a lectin during fruit body formation in basidiomycete, Pleurotus cornucopiae, the developmental process was divided into four stages: the vegetatively growing mycelium, the primordium, the immature and the mature fruit body. Hemagglutinating activity was not found in the vegetative mycelium but the activity started to appear in the primordium, and continued to increase during the fruit body formation. A protein cross-reactive with anti-lectin serum also appeared after the primordium formation, indicating that the synthesis of the lectin in P. cornucopiae was developmentally regulated.