The Journal of General and Applied Microbiology
Online ISSN : 1349-8037
Print ISSN : 0022-1260
ISSN-L : 0022-1260
MICROBIOLOGICAL HYDROXYLATION OF STEROIDS
I. MICROBIOLOGICAL HYDROXYLATION OF PROGESTERONE BY RHIZOPUS
TOSHINOBU ASAIKYOSUKE TSUDAKO AIDAEIJI OHKITOKUJI TANAKAMASAKO HATTORIHARUO MACHIDA
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1958 Volume 4 Issue 2 Pages 63-66

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Abstract
Oxidizability of progesterone was examined with 284 strains of Rhizopus sp. preserved in this Institute. Among these, 21 strains were found to have such ability. Mass culture of five of these strains was carried out and the oxidation product was identified as 11α-hydroxyprogesterone. The yield obtained was approximately 50%, using Rh. Chinensis SAITO 10-10.
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© The Microbiology Research Foundation
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