The Journal of General and Applied Microbiology
Online ISSN : 1349-8037
Print ISSN : 0022-1260
ISSN-L : 0022-1260
MICROBIOLOGICAL HYDROXYLATION OF STEROIDS
III. HYDROXYLATION OF PROGESTERONE BY SYNCEPHALASTRUM SP. (1)
TOSHINOBU ASAIKYOSUKE TSUDAKO AIDATOSHINOBU ASAITOKUJI TANAKAMASAKO HATTORI
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1958 年 4 巻 2 号 p. 79-84

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Syncephalastrum sp. was found to be capable of oxidizing progesterone to form dihydroxyprogesterone requiring a short period of incubation while trihydroxyprogesterone required a long period. These results indicated that steroids are able to be hydroxylated to trihydroxy compounds by one microorganism. The best result in oxidation was obtained by the addition of 100mg of progesterone to 100ml of the medium, dissolved in 2ml of methanol.
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© The Microbiology Research Foundation
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