抄録
Diffuse fasciitis is a disease associated with scleroderma-like induration and thickening of the skin. We report herein a case of diffuse fasciitis associated with ulcerative colitis. The patient was a 19-year-old woman with no underlying diseases. She presented with acute pain and purpura in both lower extremities. There was no obvious history of exercise or trauma, but physical examination revealed induration of the skin on both lower extremities. There was no induration of the skin of the fingers or toes, and a simple MRI of both lower legs showed inflammatory findings in the adipose tissue and fascia, leading to a diagnosis of diffuse fasciitis. A colonoscopy led to a diagnosis of a severe form of ulcerative colitis. High-dose prednisolone was administered, and induration of the skin, pain, and purpura improved. Both diffuse fasciitis and purpura were considered possible extraintestinal complications of ulcerative colitis. In diffuse fasciitis and its analog, eosinophilic fasciitis, immune abnormalities are involved in their pathogenesis. In such cases, complications associated with immune abnormalities, such as ulcerative colitis, should be considered.
