抄録
Edwardsiella tarda (E. tarda), a gram-negative bacillus, is frequently detected in aquatic environments. Although it is
mainly documented as a fish pathogen, it can also infect humans. Potential routes for human infection encompass
contaminated water or seafood ingestion and through an open wound. Patients with immunosuppressed states or specific
risk factors are more vulnerable to infections; however, case reports are limited, and no standardized guidelines
for diagnosis or treatment currently exist. This study retrospectively reviewed 19 cases of E. tarda infection at Wakkanai
City Hospital from 2013 to 2023. Enteritis, cholangitis, liver abscess, and urinary tract infection were the identified
infections. Notably, five cases progressed to sepsis. The average age of patients with sepsis was 74.4 years, and
four of them had a biliary jejunostomy history. Despite the severity of the infections, the mortality rate was 0%, with
all patients discharged alive. Patients with biliary jejunostomy were considered at a higher risk of severe illness. Although
previous studies have reported high E. tarda infection-related fatality rates, this study demonstrated improved
outcomes with timely diagnosis and appropriate treatment. Rapid identification of the causative pathogen, assessment
of risk factors, and prompt antimicrobial therapy initiation are critical in E. tarda infection management.
