Abstract
There are two important aspects in measures against nosocomial infection: one aspect is to prevent the outbreak of infection, for which thorough standard precaution should be emphasized; the other aspect is to establish a hospital environment that is robust against the emergence of drug-resistant strains, for which proper use of antibacterial agents is essential. Our committee for prevention of nosocomial infection started its initial activity of monitoring of the hospital use of antimicrobials and took subsequent measures including incorporation of an approval system for antibacterial agent use and, upon the use of vancomycin, compulsory determination of the blood concentration. The examination of changes in the drug sensitivity rate has shown a modest improvement in the past three years. This article describes the outcome of our program.
