抄録
In radiobiological studies on inhaled plutonium in experimental animals, radioactivity initially deposited on alveolar region is required for calculating absorbed dose and therefore determining dose-response relationship. To reduce the error related to variation within the sample of animals we intend to use in vivo detection of plutonium by whole body counting procedures to determine the initial alveolar deposition in each animal. The periodical in vivo counting also permits us to obtain an accurate retention curve with a small number of animals. It is concluded that the in vivo detection developed in the present work provides a powerful means to determine the initial alveolar deposition of the plutonium-exposed rats.
