Journal of Hard Tissue Biology
Online ISSN : 1880-828X
Print ISSN : 1341-7649
ISSN-L : 1341-7649
International Symposium of Maxillofacial and Oral Regenerative Biology in Okayama 2005
Comparative Study of Two Different Structures of Collagen Scaffold for Bone Formation
Andrea Paola RodriguezHitoshi NagatsukaBingzhen HuangKan RuiMika OkauchiYoshie KagawaMissana LilianaShinichiro OidaNoriyuki Nagai
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2005 年 14 巻 2 号 p. 210-211

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It has not been determined the best scaffold-structure for bone engineering. Because of this, we compared Honeycomb porous structure (HPS) and Interconnected porous structure (IPS) with or without KUSA/A1 cells implanted in mice. The transplants were subjected to radiological and histological examinations after 1,2,4 and 8 weeks of implantation.
KUSA/A1 cells alone showed small islands of new bone. Both scaffolds alone did not reveal any bone induction. KUSA/A1-HPS presented the scaffold partially filled with new bone. In contrast, KUSA/A1-IPS showed the whole scaffold filled with new bone. Our results indicated that cotton structure plays an important role in carrying the cells giving the precise size, shape and comfortable environment.
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© 2005 by The Hard Tissue Biology Network Association(JHTBNet)
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