Abstract
In this retrospectives study, we reported on 16 patients with hypopharyngeal squamous-cell carcinoma who underwent hypopharynx partial excision at the Department of Otolaryngology, Jikei University Hospital between February 2005 and February 2009. Regarding postoperative staging, two patients were at stage I, 4 patients ; stage II, 3 patients ; III, and 7 patients ; stage IV A. 7 patients had a primary cancer lesion at the piriform sinus (PS). 3 patients had at the posterior wall (PW), one patient at the post-cricoid area (PC) and 2 patients between PS and PW. We performed hypopharynx partial excision and reconstruction with free flap for all patients to conserve larynx. No patients had any troubles with swallowing and phonation postoperatively. But, four patients relapsed in cervical lymph node and one patient relapsed in primary site. These patients were underwent current chemoradiation and 2 patients died of recurrence. The cause-specific 2-year survival rate by Kaplan-Meier was 84% in all patients and 63% in stage IV A. We underwent hypopharynx partial excision for a laryngeal preservation surgery and were able to keep patient's post-operative function of the swallowing and phonation at a good condition. Moreover, only one of 16 patients relapsed at primary site, and the cause-specific 2-year survival rate was as high as 84%. Therefore, these results suggest that hypopharynx partial excision is suitable for patients with hypopharyngeal squamous-cell carcinoma as surgery with conservation of larynx.
