Abstract
Langerhans cell histiocytosis (LCH) is a very rare disease in which the number of abnormal Langerhans cells increases. We herein report two pediatric cases of LCH discovered in temporal bone lesions. The first patient was seen in our outpatient clinic due to right otorrhea. Swelling of the posterior wall of the external auditory canal was observed. A CT scan showed a soft tissue shadow with osteolysis in the bilateral temporal bones. The second patient was referred to our clinic due to swelling of the posterior wall of the right external auditory canal. A CT scan showed not only a soft tissue shadow with osteolysis in the right temporal bone, but also multiple lesions in the lungs and cervical lymph nodes. In both cases, a biopsy of the temporal bone lesion was performed under general anesthesia,and the patients were diagnosed with LCH. The administration of systemic chemotherapy in the pediatric department was effective, and both patients made satisfactory progress. When examining children with intractable otitis externa and/or mastoiditis, LCH should be considered as a possible differential diagnosis.