2018 Volume 64 Issue 3 Pages 101-107
Odontogenic myxoma (OM), which was classified by the WHO in 2017, as a benign mesenchymal tumor composed of stellate and spindle-shaped cells in an abundant myxoid stroma. OM is a rare tumor that accounts for only 1.6 − 2.7% of all odontogenic tumors. OM is distinguished from myxofibroma by the amount of collagen fibers in the tumors. We herein report a case of odontogenic myxofibroma of the maxilla. The patient was a 31-year-old man with right nasal obstruction that had been present for three months. It developed into a tumor that filled the right nasal cavity with painless swelling of the maxillary gingiva, hard palate and buccal region. CT demonstrated that the tumor was associated with the destruction of the right maxillary bone, and had spread to the maxillary sinus, nasal cavity, hard palate, ethmoid sinus, sphenoid sinus, temporal fossa and nasopharynx that was histopathologically diagnosed as myxoma by gingival incision biopsy. We performed subtotal maxillectomy by the Weber Ferguson approach. A pathological examination revealed that the tumor was composed of spindle-shaped mesenchymal cells without cytological atypia and with an abundance of collagenous fibers. Consequently, it was diagnosed as myxofibroma.