Successful treatment of severe invasive aspergillus sinusitis via an external approach with eyeball resection after allogeneic hematopoietic stem cell transplantation

Abstract

We herein report a case of life-threatening invasive fungal sinusitis following allogeneic hematopoietic stem cell transplantation. Since the infection could not be controlled by endoscopic sinus surgery or drainage of the infratemporal fossa and orbit, we performed enucleation of the left eye. Although recent case reports have described the successful preservation of eyes with invasive fungal sinusitis, we should consider orbit evisceration to save the patient's life in cases of severe immunodeficiency, such as in patients receiving multiple immunosuppressive treatments.