2018 Volume 64 Issue 6 Pages 223-227
We treated 26 cases of cervical lymph node metastasis from unknown primary sites at Kyushu University between 2007 and 2016. The N classifications of the cervical lymph nodes were as follows：N1, 1；N2, 23；N3, 2. The histopathological diagnosis of the cervical lymph nodes was squamous cell carcinoma in all cases. The 3-year overall survival rate was 52%. Seven cases showed the expression of p16 in the metastatic lymph node. The primary site was found in 5 of 7 p16 positive cases. They primary tumor sites were the tonsil, (n = 4) and the hypopharynx (n = 1). Further study usingof a larger cohort is therefore needed.
