A case of sinosnasal amyloidosis

Abstract

Amyloidosis is a disease caused by the accumulation of protein with a specific fiber structure known as amyloid. We herein report a case of localized sinonasal amyloidosis, which is a very rare disease. The patient was a 47-year-old man who complained of nasal obstruction and recurring epistaxis on his right side. Computed tomography and magnetic resonance imaging showed a soft tissue shadow in his right paranasal sinus. Endoscopic sinus surgery was carried out, and the lesion was pathologically found to be amyloidosis. Since he had no disorder in other tissues or organs, he was diagnosed with localized sinonasal amyloidosis. The characteristic calcification of sinonasal amyloidosis has been called “fluffy calcifications” in some reports, which was also seen in this case. “Fluffy calcifications” may be the specific sign of sinonasal amyloidosis.